Body fat distribution and insulin resistance

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Body Fat Distribution and Insulin Resistance

The burden of obesity has increased globally over the last few decades and its association with insulin resistance and related cardio-metabolic problems have adversely affected our ability to reduce population morbidity and mortality. Traditionally, adipose tissue in the visceral fat depot has been considered a major culprit in the development of insulin resistance. However, there is a growing ...

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Our aim was to critically evaluate the relations among smoking, body weight, body fat distribution, and insulin resistance as reported in the literature. In the short term, nicotine increases energy expenditure and could reduce appetite, which may explain why smokers tend to have lower body weight than do nonsmokers and why smoking cessation is frequently followed by weight gain. In contrast, h...

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Subcutaneous Adipose Cell Size and Distribution: Relationship to Insulin Resistance and Body Fat

OBJECTIVE Metabolic heterogeneity among obese individuals may be attributable to differences in adipose cell size. We sought to clarify this by quantifying adipose cell size distribution, body fat, and insulin-mediated glucose uptake in overweight to moderately-obese individuals. METHODS A total of 148 healthy nondiabetic subjects with BMI 25-38 kg/m2 underwent subcutaneous adipose tissue bio...

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Associations between body fat distribution, insulin resistance and dyslipidaemia in black and white South African women

AIM The aim was to examine differences in body fat distribution between premenopausal black and white South African (SA) women and explore the ethnic-specific associations with cardiometabolic risk. METHODS Body composition, using dual-energy X-ray absorptiometry (DXA) and computerised tomography, insulin resistance (HOMA-IR) and lipid levels were assessed in 288 black and 197 white premenopa...

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Insulin resistance, body composition, and fat distribution in obese children with nonalcoholic fatty liver disease.

BACKGROUND AND OBJECTIVES The aim of this study was to evaluate the influence of body composition, especially distribution of body fat, and insulin resistance on nonalcoholic fatty liver disease (NAFLD) in obese children. METHODS AND STUDY DESIGN One hundred obese children (66 boys, 34 girls) with (n=60) and without NAFLD (n=40) were assessed. Anthropometry, laboratory tests, abdominal ultras...

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ژورنال

عنوان ژورنال: Journal of Endocrinology, Metabolism and Diabetes of South Africa

سال: 2005

ISSN: 1608-9677,2220-1009

DOI: 10.1080/22201009.2005.10872130